Maintain an index of many of the goods you employ (together with prescription/nonprescription medicine and herbal solutions) and share it along with your doctor and pharmacist. Usually do not get started, stop, or change the dosage of any medicines without having your health care provider's acceptance.
Observational scientific tests have shown that concomitant usage of opioid analgesics and benzodiazepines increases the danger of drug-relevant mortality as compared to utilization of opioids by yourself.
This can be associated with a minimize in efficacy, and in some sufferers, might lead to indications and signs of opioid withdrawal.
Signs and indicators of overdosage with promethazine HCl vary from gentle despair from the central anxious system and cardiovascular process to profound hypotension, respiratory despair, unconsciousness, and sudden Dying.
Youngsters could possibly be additional delicate on the Uncomfortable side effects of the drug, Particularly slowed respiration and uncontrolled movements (see also Warning portion). Young children may also working experience excitability as an alternative to drowsiness.
Take into account that this medication has become prescribed mainly because your health care provider has judged which the advantage to you is larger than the chance of side effects. Lots of people utilizing this medication do not have severe Unintended effects.
There are actually differing kinds of narcotic remedies (opioids) for discomfort. If you're taking more than one style simultaneously, you will have additional side effects.
Your mouth may perhaps get dry. Chewing sugarless gum or sucking tricky candy and ingesting lots of drinking water may perhaps aid. Make contact with your care group if the problem doesn't go away or is significant.
The mix of promethazine hydrochloride and codeine phosphate really should be employed with caution in pediatric sufferers 6 several years and older (see Warnings-Use in Pediatric Patients).
Codeine is modified into a powerful opioid drug (morphine) in The body. In many people, this variation occurs faster and a lot more completely than typical, which enhances the risk of pretty significant Unintended effects.
Propulsive peristaltic waves within the colon are decreased, whilst tone can be improved to The purpose of spasm resulting in constipation. Other opioid-induced effects may well contain a discount in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.
Inform your treatment workforce if your pain does not disappear, if it will get worse, or In case you have new or a special sort of suffering.
This medication can dry up and thicken mucus as part of your lungs, rendering it tougher to breathe and apparent your lungs. That can help protect against this outcome, consume loads of fluids Except if usually directed by your health practitioner.
are pregnant or strategy to become pregnant. Promethazine Hydrochloride and Codeine Phosphate Oral Answer can damage your unborn child. See “Precisely what is The most crucial facts I should know about Promethazine Hydrochloride and Promethazine codeine syrup Codeine Phosphate Oral Option?” are breastfeeding or plan to breastfeed. Codeine passes into your breast milk and could potentially cause major side effects in your toddler which includes increased sleepiness, respiratory problems (respiratory despair), and death. It's not at all acknowledged if promethazine can pass into your breast milk.